Humans are wired to fear the unknown. That’s why uncertainty—whether at the macro level of a global economic, health, or geopolitical crisis or at the micro level (Will I get that job? Will this venture be successful? Am I on the right career path?)—can feel nerve-racking, exhausting, and even debilitating. However, that gut reaction leads people to miss a crucial fact: Uncertainty and possibility are two sides of the same coin.

A version of this article appeared in the July–August 2022 issue of Harvard Business Review.